Table 1. Distribution of the five SNPs studied in ERAP1 according to a recessive model of the minor allele.
SNP | MA | TEST | Patients | Controls | p | OR |
rs27044 | G | GG/CC+CG | ||||
Whole group | 46/316 | 51/409 | 0.5 | 1.2 | ||
HLA-B Risk factor group | 24/154 | 7/77 | 0.2 | 1.7 | ||
rs17482078 | T | TT/CC+CT | ||||
Whole group | 17/344 | 12/446 | 0.1 | 1.8 | ||
HLA-B Risk factor group | 6/172 | 1/83 | 0.3 | 2.8 | ||
rs10050860 | T | TT/CC+CT | ||||
Whole group | 17/344 | 12/446 | 0.1 | 1.8 | ||
HLA-B Risk factor group | 6/172 | 1/83 | 0.3 | 2.8 | ||
rs30187 | T | TT/CC+CT | ||||
Whole group | 70/292 | 73/386 | 0.2 | 1.3 | ||
HLA-B Risk factor group | 39/137 | 13/71 | 0.2 | 1.5 | ||
rs2287987 | C | CC/TT+CT | ||||
Whole group | 17/344 | 12/446 | 0.1 | 1.8 | ||
HLA-B Risk factor group | 6/172 | 1/83 | 0.3 | 2.8 |
Individuals with the HLA-B risk factors are subjects bearing HLA-B*51 and/or B*57.