Table 2.

Non-invasive vascular reactivity and hemodynamic measurements, pre- to completion of (end) bed rest analysis, N=5

	Pre- BR	End- BR	p-value*
Brachial artery FMD
Baseline diameter, mm	4 ± 1	4 ± 1	0.09
Baseline velocity, m/s	0.2 ± 0.1	0.2 ± 0.1	0.56
Baseline flow, mL/s	112 ± 47	130 ± 95	0.74
Baseline shear stress	13 ± 6	16 ± 6	0.41
Reactive hyperemia diameter, mm	4 ± 1	4 ± 1	0.06
Reactive hyperemia velocity, m/s	1 ± 0.4	1 ± 0.2	0.67
Reactive hyperemia flow, mL/s	1,058 ± 401	874 ± 288	0.22
Reactive hyperemia shear stress	86 ± 30	89 ± 29	0.72
Flow-mediated vasodilation, FMD (%)	11 ± 3	9 ± 2	0.04
Femoral artery FMD
Baseline diameter, mm	6 ± 1	5 ± 1	0.15
Baseline velocity, m/s	0.2 ± 0.1	0.2 ± 0.1	0.77
Baseline flow, mL/s	244 ± 76	241 ± 131	0.96
Baseline shear stress	8 ± 4	8 ± 2	0.58
Reactive hyperemia diameter, mm	6 ± 0.1	6 ± 1	0.06
Reactive hyperemia velocity, m/s	0.4 ± 0.2	1 ± 0.1	0.40
Reactive hyperemia flow, mL/s	709 ± 352	648 ± 96	0.79
Reactive hyperemia shear stress	17 ± 8	26 ± 12	0.19
Flow-mediated vasodilation, FMD (%)	4 ± 1	2 ± 1	0.04
Applanation Tonometry
Central Augmentation Index (Aix), %	−4 ± 9	5 ± 11	0.03
Central Aix, 75BPM**, %	−15 ± 11	−6 ± 11	0.05
Carotid-Femoral	5 ± 1	5 ± 1	0.09
Pulse-Wave Velocity, m/s
Hemodynamics
Heart rate, bpm	53 ± 11	52 ± 7	0.97
SBP, mm Hg	113 ± 14	110 ± 19	0.52
DBP, mm Hg	58 ± 7	62 ± 7	0.02

^*p-value calculated from paired t-test.

^**Central Augmentation Index is adjusted for heart rate, at 75 beats per minute.