Table 2.
Hp phenotype and abnormal UAD at the first exam
| Outcome | Hp 1-1 (n = 449) |
Hp 2-1 (n = 1025) |
Hp 2-2 (n = 661) |
OR (95% CI) |
pa | |
|---|---|---|---|---|---|---|
| Hp 1-1 | Hp 2-1 | |||||
| Any Notchb | 70/433 (16.2%) |
158/1004 (15.7%) |
95/651 (14.6%) |
1.29 (0.91, 1.82) |
1.18 (0.89, 1.57) |
0.32 |
| Bilateral Notchc | 27/435 (6.2%) |
63/1007 (6.3%) |
36/652 (5.5%) |
1.19 (0.70, 2.01) |
1.18 (0.77, 1.81) |
0.72 |
| RI >90th Percentilea | 38/449 (8.5%) |
108/1025 (10.5%) |
61/661 (9.2%) |
0.87 (0.56, 1.34) |
1.19 (0.85, 1.66) |
0.28 |
| PI >90th Percentiled | 41/448 (9.2%) |
107/1023 (10.5%) |
65/661 (9.8%) |
0.89 (0.58, 1.36) |
1.06 (0.76, 1.48) |
0.67 |
Values are n/total (%), or OR (95% CI) with Hp 2-2 as the reference group. Abbreviations: OR, odds ratio; CI, confidence interval.
Adjusted for age, gestational age at Doppler exam, race, education, vitamin use, pre-pregnancy BMI and treatment group. 38 women with missing pre-pregnancy BMI data were excluded from all models.
Nine women with missing data for any notch were excluded. Only 323 of the 334 women with notching are included in the table, as 8 women had the 2-1M phenotype and 3 women were missing pre-pregnancy BMI.
Three women with missing bilateral notch data were excluded.
Multiples of the median for the RI and PI were calculated to determine whether values exceeded the 90th percentile for gestational age.