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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Kidney Int. 2012 Dec 12;83(3):426–437. doi: 10.1038/ki.2012.379

Figure 2. Pacsin 2 expression in the nephrogenic zone and in newborn and adult mouse kidney glomerulus.

Figure 2

(a) Confocal images showing apical Pacsin 2 expression in the tips of ureteric bud–derived structures, but not in S-shaped bodies or renal vesicles. DAPI, 4’,6-diamidino-2-phenylindole; g, glomerulus; rv, renal vesicle; s, S-shaped body; ub, ureteric bud. (b) In newborn mouse kidneys (1–2), Pacsin 2 is weakly expressed in the parietal epithelial cells of the Bowman’s capsule and in the glomerular tufts. (3–6) There is a remarkable upregulation of Pacsin 2 in adult 3-month-old kidneys. (5–6) Confocal images showing the strong expression of Pacsin 2 on the plasma membrane of podocytes of the glomerular tufts, which were labeled by WT1 staining. Bar = 50 μm.