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Immunohistochemical anaylsis of JmjC domain–containing histone demethylase 2A (JHDM2A) in mouse testis. JHDM2A (green) is highly expressed in round spermatids (RS) and not quite merged with gamma histone 2A variant X (γH2AX)-positive (red) spermatogonia (SG) and spermatocytes (SC). JHDM2A-positive signals disappear in elongated spermatids (ES). Cytoplasmic staining of JHDM2A is observed in Sertoli cells (S). Hoechst (DNA) staining is shown as blue.
