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Impaired spermiogenesis in JmjC domain–containing histone demethylase 2A (Jhdm2a) knockout mice. (A) Abnormal spermatids at step 15 of spermiogenesis. Smaller, round-shaped spermatids are observed in the knockout mice. (B) Ultrastructurally, chromatin condensation is incomplete in the knockout spermatids. Bar = 1 μm.
