Figure 2. The distribution of embryo ploidy based on patients FMR1 sub-genotype.

FMR1 mutations were not statistically associated with embryo ploidy, though the high aneuploidy rate in biallelic low, hom-low/low women is quite remarkable. Lack of significance may in here-reported findings, therefore, be consequence of small patient numbers. Also of interest is the very low aneuploidy rate in women with one low and one high allele, presenting with only approximately half the aneuploidy rate of even norm women. While these findings, dues to small patient numbers, also need to be viewed with caution, they could suggest a compensatory benefit from a high allele on negative effects of a low allele.