. Author manuscript; available in PMC: 2014 Jul 15.

Published in final edited form as: J Acquir Immune Defic Syndr. 2010 Apr 1;53(4):451–455. doi: 10.1097/QAI.0b013e3181cb8319

TABLE 4.

Association Between NRD and Previously Reported Associations MtDNA Haplogroup and AIDS Progression in Untreated Patients²² and With Lipoatrophy²⁴ and Peripheral Neuropathy²⁵ in Patients on HAART

	f (%)	n (affected)	HR	95% CI	P
IWX	8.1	25 (2)	0.52	(0.12 to 2.19)	0.328
W	2.9	9 (0)	Undefined	—	0.124
U5a1-15218	3.6	11 (0)	Undefined	—	0.046
Uk	10.5	32 (6)	1.27	(0.53 to 3.01)	0.604
J	9.7	29 (1)	0.20	(0.03 to 1.48)	0.039
T	11.7	35 (7)	1.46	(0.65 to 3.28)	0.382
H	41.8	130 (21)	1.12	(0.62 to 2.02)	0.704
H1	12.6	39 (7)	1.14	(0.50 to 2.00)	0.763
H3	3.9	12 (0)	Undefined	—	0.028
H4	2.3	7 (2)	1.56	(0.37 to 6.56)	0.567
H5	2.3	7 (1)	0.88	(0.12 to 6.48)	0.896

Bold values are significant at α = 0.05.

Only AIDS associations reported as “strong” by Hendrickson et al²² (ie, the haplogroups were consistently significant in greater than 2 tests) are shown.