Skip to main content
. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Clin Cancer Res. 2014 Mar 25;20(11):2873–2884. doi: 10.1158/1078-0432.CCR-14-0205

Figure 5.

Figure 5

Independent validation of OCAMP-B and development of a clinical assay for stratification of OSCCs (A) An independent UPENN dataset is classified with high accuracy (21/22 tumors) by OCAMP-B weighted voting (WV output) with respect to lymph node metastatic status (Path= known pathologic status), (B) Schematic illustrating the selection of 42 OCAMP genes and SVM processing on training set samples to identify the best discriminating genes. The final 19-gene list for FFPE is on right with asterisks on 10-gene list for fresh specimens. (C) Discriminant scores from SVM analysis showing successful stratification in 12/13 FFPE and 17/18 fresh biopsy test cases of metastatic nodal disease using a qRT-PCR assay.