Table 2.
Body Fluid Compartment |
Decrease in Volume of Respective Compartment (mL) | ||||
---|---|---|---|---|---|
| |||||
Acute Blood Loss |
Slow Blood Loss |
Isotonic Fluid |
Pure Water | Half-Isotonic Fluid |
|
| |||||
Intracellular | 400 | 400 | 0 | 550 | 275 |
| |||||
Extracellular | 600 | 600 | 1000 | 450 | 725 |
Interstitial | 0 | 1250 | 750 | 375 | 562.5 |
Plasma | 600 | −650* | 250 | 75 | 162.5 |
| |||||
Blood | 1000 | 250 | 250 | 125 | 187.5 |
| |||||
Hct (%) | 40 | 33.7 | 42.1 | 40 | 41 |
| |||||
Δ Serum Na+ | 0 | 0 | 0 | ⇑ 3.6 mEq/L | ⇑ 1.8 mEq/L |
Assuming TBH2O = 40L, blood volume = 5L, baseline % Hct = 40 & serum Na+ = 140 mEq/L
Transcapillary refill expands plasma volume at the expense of interstitial fluid in the setting of slow blood loss.