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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Pharmacol Biochem Behav. 2013 Sep 5;111:120–127. doi: 10.1016/j.pbb.2013.08.013

Figure 1.

Figure 1

Treatment regimen for cannabidiol neuroprotection studies. Rats were administered ethanol according to a 4-day binge paradigm (A). In addition to receiving ethanol, rats were co-administered CBD by IP injection twice daily (filled arrows) or topical gel formulation daily (open arrows). Plasma samples were collected on day 3 and prior to euthanasia from tail vein blood or trunk blood, respectively, for determination of blood ethanol concentrations and plasma CBD concentrations. Experiment groups with number of animals (B). Groups with matching symbols were collapsed prior to analysis.