Figure 8. Short- and long-term changes in levels of transcripts encoding IL-6 (A), IL-1β (B), TNF-α (C) and IL-10 in dorsal root ganglia and spinal tissues in spinal cord-transected rats.
Real-time RT-qPCR determinations were made in T6–T8 and T9–T11 dorsal root ganglia and T6–T8 and T9–T11 spinal segments at day (D) 2, 15 or 60 (abscissa) after spinal cord transection at T8–T9 level. Data are expressed as the ratio of specific mRNA over GaPDH mRNA [R.Q.(A.U.)]. Each bar is the mean + S.E.M. of n independent determinations (D2, D15: n = 6; D60: n = 12). Sham values at every postoperative time are pooled under “C” (control) on abscissa. * P<0.05, * P<0.01, *** P<0.001 compared to respective values in sham-operated rats (C). Two-way ANOVA followed by Bonferroni test.