Table 2. Literature Review - Gastrointestinal Bleeding as a Result of Kaposi Sarcoma - Presentations, Treatments and Outcomes.
Author | Year | Age/ Gender |
Presentation | History | GI Location | Treatment | Outcome |
---|---|---|---|---|---|---|---|
Salako Abdulkadir14 | 2005 | 56 yo / M | melena | h.pylori s/p treatment | jejunum, ileum | small bowel resection | death from rupture of hepatic kaposi, HIV testing negative |
Ablin41 | 1998 | 73 yo / M | melena, fever | vasculitis on immunosuppressants | gastric, LI, rectum | vinblastine, cessation of immunosuppressants | continued hemorrhage, death |
Balachandra42 | 2006 | 61 yo / M | GI bleeding | Inuit, NSAID use | stomach, ileocecal valve | doxorubicin | alive at 2.5 yrs HIV testing negative |
Bryk43 | 1978 | 78 yo / M | weakness, malaise, melena | Known Cutaneous Kaposi | duodenum, jejunum | local radiotherapy, vinblastine, cyclophosphamide | death from continued bleeding |
Calzona44 | 2002 | 15 yo / F | melena, lymphadenopathy, fever | Renal Txp | stomach | cessation of immunosuppressive therapy | bleeding stopped at 16 days, remission at 6 months |
Cairncross45 | 2009 | 5 yo / F | “massive GI bleed” | HIV, CD4 14 | unknown | none | Death |
De Blasio46 | 2005 | 42 yo / M | anemia, lymphadenopathy | renal txp | gastric, liver, inguinal lymph nodes | sub-total gastrectomy | death few days following surgery |
Lin47 | 2002 | 41 yo / F | lymphadenopathy, tarry stools | Renal Txp | Esophagus, stomach | none listed | Unknown |
Kahl48 | 2007 | 39 yo | hematochezia | none | stomach, SI, LI | none listed | New HIV Dx |
Neville12 | 1996 | 53 yo / M | melena, anemia | HIV, known cutaneous KS | SI | chemo, radiation | resolution of symptoms |
Potter49 | 1984 | 35 yo / M | hematochezia, abdominal distention | Known HIV / AIDS | esophagus, duodenum, SI, appendix, LI, Liver, GB, pancreas | TPN, bowel rest, vinblastine, adriamycin, bleomycin, vincristine, actinomycin, DTIC | progression of kaposi, death due to respiratory failure (PCP) |
Rodriguez10 | 2012 | 30 yo / M | anal pain, hematemesis | HIV, known cutaneous KS | stomach, duodenum, rectum | HAART, doxorubicin, radiation | unknown |
Stribling51 | 1978 | 59 yo / M | skin lesions, GI bleed | Renal Txp | Esophagus, stomach, SI, LI, liver, adrenals, retroperitoneum | Laparotomy, bowel resection | Death |
Wien52 | 1991 | 66 yo / M | upper GI bleed | alcoholic liver disease | stomach | radiation | resolution of gastric lesions |
Yildiz53 | 2010 | 52 yo / M | growing palate mass, melena, hematemesis | known cutaneous classic KS, HIV negative | palate, esophagus, stomach, lung, liver | Adriablastine, vincristine, bleomycin | partial remission |
Pub Med and Google Scholar searches for “gastrointestinal bleeding AND Kaposi”.
Location Abbreviations: SI = Small Intestine, LI = Large Intestine, GB = gall bladder