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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Biochem Pharmacol. 2012 Sep 14;84(12):1571–1580. doi: 10.1016/j.bcp.2012.09.005

Fig. 1.

Fig. 1

Apigenin induces DNA damage in leukemia cells. (A) Comet assays of THP-1 cells treated with indicated concentrations of apigenin or diluent DMSO for 3 h or with 1 mM H2O2 for 1 h. (B) % Tail DNA determined by alkaline comet assay in cells treated as described in (A). (C) % Tail DNA in cells treated with 50 μM apigenin for different lengths of time or diluent DMSO for 9 h. (D) Caspase-3 activity was determined in cells treated as described in (C). Data represents mean ± SEM, n = 3. *p < 0.05, **p < 0.01, compared to DMSO control.