Table 3. Cox regression analysis of no or low (< 10,000 copies/mL, n = 74) versus high (≥ 10,000 copies/mL, n = 51) peak viremia within the first 100 days and transplant outcomes (n = 125).
| Sustained Engraftment* at 100 Days | Day 100 II-IV aGVHD | Day 100 TRM | 1-Yr DFS | ||
|---|---|---|---|---|---|
| Neutrophils | Platelets | ||||
| HR for ≥ 10,000 Viremia (95% CI) | 0.98 (0.68-1.41) | 1.01 (0.68-1.50) | 1.41 (0.86-2.31) | 1.04 (0.51-2.13) | 0.71 (0.39-1.30) |
| P value | 0.92 | 0.95 | 0.17 | 0.90 | 0.27 |
aGVHD indicates acute graft-versus-host disease; TRM, transplant related mortality; DFS, disease free survival; HR, hazard ratio; CI, confidence interval.
Estimate incorporates speed and success of neutrophil and platelet engraftment (speed and success).