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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Mol Microbiol. 2014 Feb 8;91(5):976–995. doi: 10.1111/mmi.12509

Fig. 5. EmrA1 mutant of F. tularensis is attenuated for virulence and its virulence is restored in gp91Phox−/− mice.

Fig. 5

Survival of C57BL/6 mice (n = 5) infected intranasally with 1×105 (A) and 1×106 CFU (B) of F. tularensis LVS or the emrA1 mutant and observed for mortality.

C57BL/6 wild type mice or gp91Phox−/− mice (n=3) were infected intranasally with 1×105 (C) and 1×106 CFU (D) of the emrA1 mutant. The data from a single experiment are shown. The mice were observed for the indicated periods for morbidity and mortality. The results are expressed as Kaplan-Meier survival curves and the P values were determined using Log-rank test.