. Author manuscript; available in PMC: 2014 Jul 15.

Published in final edited form as: J Rheumatol. 2013 Apr 1;40(6):809–817. doi: 10.3899/jrheum.121012

Table 3.

Predictors of time to CV event, excluding those with prior CV events, using multivariate Cox regression.

Variable	HR (95% CI)	p
MTHFR A1298C; ≥ 1 copy minor allele	1.28 (0.71, 2.32)	0.414
MTHFR C677T; ≥ 1 copy minor allele	1.07 (0.59, 1.93)	0.832
Education	0.84 (0.76, 0.94)	0.003
Diabetes	0.43 (0.19, 0.96)	0.039
Modified Charlson-Deyo index	1.26 (1.12, 1.42)	< 0.0001
ACPA	4.59 (1.10, 19.08)	0.036

MTHFR: methylenetetrahydrofolate reductase; ACPA: anticitrullinated protein antibody; CV: cardiovascular.