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. 2014 Jul 15;2:48. doi: 10.3389/fchem.2014.00048

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Copyright © 2014 Conde, Dias, Grazú, Moros, Baptista and de la Fuente.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Click chemistry reaction. The copper-catalyzed cycloaddition of azides and alkynes (CuAAC) developed for click chemistry joins an organic azide (N₃) and alkyne together producing a mixture of 1,4- and 1,5-triazoles.