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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Shock. 2009 Jul;32(1):17–22. doi: 10.1097/shk.0b013e3181997173

Fig. 4. Plasma HMGB1 levels trend higher in patients requiring longer ICU stays.

Fig. 4

Patients requiring ICU LOS greater than 14 days had consistently higher plasma HMGB1 levels than did patients requiring ICU LOS less than or equal to 14 days. This trend was most apparent during the first 24 h after injury; however, in this small study population, it did not reach statistical significance (mixed model, 0.499) and requires further investigation.