Table 4.
Statistical results of relationships between PLAGL2 expression and various clinicopathologic characteristics in colorectal cancer
| Variables | Total | Low (%) | High (%) | P-value |
|---|---|---|---|---|
|
|
||||
| 225 | 14 | 211 | ||
| Age at surgery (years) | ||||
| ≤60 | 79 | 5 | 74 | 0.961 |
| >60 | 146 | 9 | 137 | |
| Gender | ||||
| Male | 126 | 10 | 116 | 0.230 |
| Female | 99 | 4 | 95 | |
| Pathophysiologic features | ||||
| Tumor size (cm) | ||||
| ≤5 | 116 | 8 | 108 | 0.666 |
| >5 | 109 | 6 | 103 | |
| Tumor location | ||||
| Rectum | 136 | 9 | 127 | 0.761 |
| Colon | 89 | 5 | 84 | |
| Histological type | ||||
| WD/MD | 168 | 12 | 156 | 0.326 |
| PD | 57 | 2 | 55 | |
| T stage | ||||
| T1/2 | 70 | 8 | 62 | 0.030* |
| T3/4 | 155 | 6 | 149 | |
| Lymph node metastasis | ||||
| Negative | 138 | 7 | 131 | 0.369 |
| Positive | 87 | 7 | 80 | |
| M stage | ||||
| M0 | 219 | 14 | 205 | 0.552 |
| M1 | 6 | 0 | 6 | |
| Lymphatic invasion | ||||
| Negative | 206 | 13 | 193 | 0.856 |
| Positive | 19 | 1 | 18 | |
| Tumor stage | ||||
| I | 58 | 5 | 53 | 0.312 |
| IIa, IIb, IIc | 79 | 2 | 77 | |
| IIIa, IIIb, IIIc | 82 | 7 | 75 | |
| IVa, IVb | 6 | 0 | 6 | |
*
Indicated statistical significance (P<0.05).