Table 5.
Statistical results of relationships between PLAGL2 expression and various clinicopathologic characteristics in gastric cancer
| Variables | Total | Low (%) | High (%) | P-value |
|---|---|---|---|---|
|
|
||||
| 286 | 23 | 263 | ||
| Age at surgery (years) | ||||
| ≤60 | 157 | 9 | 148 | 0.113 |
| >60 | 129 | 14 | 115 | |
| Gender | ||||
| Male | 211 | 20 | 191 | 0.134 |
| Female | 75 | 3 | 72 | |
| Pathophysiologic features | ||||
| Tumor size (cm) | ||||
| ≤5 | 168 | 9 | 159 | 0.046* |
| >5 | 118 | 14 | 104 | |
| Tumor location1 | ||||
| Upper | 31 | 5 | 26 | 0.087 |
| Middle | 46 | 1 | 45 | |
| Lower | 208 | 17 | 191 | |
| Histological grade | ||||
| Well differentiation | 29 | 2 | 27 | 0.293 |
| Moderate differentiation | 41 | 2 | 39 | |
| Poor differentiation | 208 | 17 | 191 | |
| Undifferentiation | 8 | 2 | 6 | |
| Growth pattern2 | ||||
| Expanding | 67 | 4 | 63 | 0.317 |
| Intermediate | 90 | 5 | 85 | |
| infiltrative | 122 | 13 | 109 | |
| T stage | ||||
| T1 | 25 | 0 | 25 | 0.119 |
| T2 | 45 | 5 | 40 | |
| T3 | 154 | 16 | 138 | |
| T4 | 62 | 2 | 60 | |
| N stage | ||||
| N0 | 74 | 4 | 70 | 0.243 |
| N1 | 36 | 4 | 32 | |
| N2 | 71 | 3 | 68 | |
| N3 | 105 | 12 | 93 | |
| M stage | ||||
| Negative | 203 | 14 | 189 | 0.265 |
| Positive | 83 | 9 | 74 | |
| Lymphatic invasion | ||||
| Negative | 208 | 19 | 189 | 0.267 |
| Positive | 78 | 4 | 74 | |
| General classification3 | ||||
| Borrmann 1 | 3 | 1 | 2 | 0.137 |
| Borrmann 2 | 31 | 0 | 31 | |
| Borrmann 3 | 202 | 20 | 182 | |
| Borrmann 4 | 24 | 2 | 22 | |
| Tumor stage | ||||
| I/II | 97 | 6 | 91 | 0.408 |
| III/IV | 189 | 17 | 172 | |
1
one case didn’t report the tumor location.
2
seven cases didn’t report the growth pattern.
3
Twenty-sixe patients were diagnosed with early gastric cancer.
*
Indicated statistical significance (P<0.05).