Table 7.
Survival analysis in gastric cancer
Univariate | Multivariate | |||||
---|---|---|---|---|---|---|
|
||||||
Variable | Total (%) | 5 years (%) | P-value | RR | 95% CI | P-value |
Age at surgery (years) | ||||||
≤60 | 157 | 61.8 | 0.428 | |||
>60 | 129 | 54.8 | ||||
Gender | ||||||
Male | 211 | 72.4 | 0.612 | |||
Female | 75 | 46.7 | ||||
Pathophysiologic features | ||||||
Tumor size (cm) | ||||||
≤5 | 168 | 64.8 | <0.001* | 0.983 | 0.691-1.400 | 0.925 |
>5 | 118 | 49.7 | ||||
Tumor location1 | ||||||
Upper | 31 | 33.5 | 0.134 | |||
Middle | 46 | 43.5 | ||||
Lower | 208 | 71.2 | ||||
Histological grade | ||||||
Well/Moderate differentiation | 70 | 49.3 | 0.634 | |||
Poor differentiation | 216 | 73.1 | ||||
Growth pattern2 | ||||||
Expanding | 67 | 58.2 | 0.287 | |||
Intermediate | 90 | 48.9 | ||||
infiltrative | 122 | 51.3 | ||||
T stage | ||||||
T1 | 25 | 70.0 | <0.001* | 0.555 | 0.380-0.811 | 0.002* |
T2 | 45 | 77.8 | ||||
T3 | 154 | 61.5 | ||||
T4 | 62 | 21.0 | ||||
N stage | ||||||
N0 | 74 | 85.1 | <0.001* | 0.449 | 0.301-0.671 | <0.001* |
N1 | 36 | 71.2 | ||||
N2 | 71 | 46.5 | ||||
N3a/3b | 105 | 42.9 | ||||
M stage | ||||||
Negative | 203 | 71.8 | <0.001* | 0.667 | 0.453-0.981 | 0.039* |
Positive | 83 | 32.4 | ||||
Lymphatic invasion | ||||||
Negative | 208 | 71.5 | 0.001* | 0.798 | 0.556-1.145 | 0.221 |
Positive | 78 | 35.9 | ||||
General classification3 | ||||||
Borrmann 1 | 3 | 66.7 | <0.001* | 0.654 | 0.393-1.089 | 0.102 |
Borrmann 2 | 31 | 70.8 | ||||
Borrmann 3 | 202 | 70.7 | ||||
Borrmann 4 | 24 | 20.8 | ||||
Tumor stage | ||||||
I/II | 97 | 88.5 | <0.001* | 0.456 | 0.182-1.143 | 0.094 |
III/IV | 189 | 69.8 | ||||
PLAGL2 expression | ||||||
Low | 23 | 39.1 | 0.137 | |||
High | 263 | 77.5 |
one case didn’t report the tumor location.
seven cases didn’t report the growth pattern.
Twenty-sixe patients were diagnosed with early gastric cancer.
Indicated statistical significance (P<0.05).