Figure 5.
Knockdown of FOXC1 inhibited cell proliferation, migration, invasion abilities in KYSE30. A: Si-FOXC1-2 remarkably inhibited the KYSE30 cell proliferation compared with siNC in MTS assay (P < 0.05). B: The colony formation rate of si-FOXC1-2 was significantly decreased compared with siNC (P < 0.05). C, D: Both scratch wound healing assay and migration assay proved that knockdown of FOXC1 inhibited cell migration by 52% and 54% respectively. E: The silence of FOXC1 evidently impaired the capacity of cell invasion in the Matrigel substrate (P < 0.05).