Table 1. Vesicle competition model parameters. ^(a,b)Area and volume of 120 nm diameter sphere. ^(c) reported in²⁴. ^(d) Close to 80 μM value reported for oleate vesicles¹⁵. ^(e) Bicine buffer concentration used experimentally¹⁵,¹⁷. ^(f) See Supplementary Material for rationale. ^(g) Reported in³³. ^(h) Considered similar to POPC head area reported in³³. ⁽ⁱ⁾ Calculated from equation (13); same for spherical and deflated vesicles. ^(j) Calculated as: where , and .

Parameter	Description	Value	Unit
	Inside/ouside surface area of extruded model vesicles(a)	4.524 × 104	nm2
	Volume of model vesicles, spherical when extruded(b)	9.048 × 105	nm3
	Volume of model vesicles, deflated when extruded(c)	8.595 × 105	nm3
	Critical vesicle concentration for oleic acid(d)	6.667 × 10−5	M
[B]	Buffer concentration(e)	0.2	M
kout	OA lipid release constant(f)	7.6 × 10−2	s−1
kin	OA lipid uptake constant(f)	7.6 × 103	s−1M−1nm−2
αL	OA lipid head area(g)	0.3	nm2
αP	DOPA lipid head area(h)	0.7	nm2
	OA monomer equilibrium concentration, for pure OA vesicle(i)	6.667 × 10−5	M
	OA monomer equilibrium concentration, for DOPA:OA (ρ0 = 0.1, d = 0) vesicle(i)	5.297 × 10−5	M
NOA	Aggregation number for extruded pure OA vesicle(j)	301592
NDOPA:OA	Aggregation number for extruded DOPA:OA (ρ0 = 0.1, d = 0) vesicle(j)	266111