Table 1.

Mean laboratory values for six sheep supported on the BioVAD circulatory support device. P value determined by ANOVA.

Laboratory Value	Baseline	Day 1	Day 2	Day 3	Day 4	Day 5	P value
Plasma free hemoglobin (mg/dL)a	2.1 ± 1.6	4.4 ± 4.1	3.5 ± 2.7	2.4 ± 1.8	2.6 ± 1.9	1.2 ± 0.4	0.002
Platelets (K/mm3)b	223 ± 143	142 ± 85	108 ± 64	128 ± 72	182 ± 179	232 ± 245	0.05
Lactic acid (mmol/L)c	1.8 ± 0.9	1.2 ± 0.8	0.7 ± 0.3	0.5 ± 0.2	0.5 ± 0.2	0.5 ± 0.3	0.002
Creatinine (mg/dL)d	1.0 ± 0.2	1.0 ± 0.3	0.9 ± 0.6	0.7 ± 0.1	0.7 ± 0.1	0.7 ± 0.1	<0.001
Total bilirubin (mg/dL)e	0.1 ± 0.08	0.3 ± 0.16	0.2 ± 0.15	0.2 ± 0.11	0.2 ± 0.08	0.2 ± 0.08	0.46
Hemoglobin (g/dL)f	7.2 ± 0.7	6.9 ± 1.1	6.6 ± 0.7	6.7 ± 0.7	6.7 ± 0.8	6.3 ± 0.8	0.91

Reference ranges:

^a1.0-8.0 m/dL;

^b250-750 K/mm³;

^c0.5-2.2 mmol/L;

^d1.2-1.9 mg/dL;

^e0.1-0.5 mg/dL;

^f9.0-15.0 mg/dL