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. 2014 Jul;21(7):982–988. doi: 10.1128/CVI.00235-14

TABLE 1.

Between-assay correlations in absolute pneumococcal antibody levelsa

Laboratory comparison and serotype r Slope (95% CIb) Intercept Biasc % bias nd
A vs C
    1 0.9599 0.979 (0.913 to 1.046) −0.057 −0.176 −3.1 71
    3 0.8725 0.833 (0.733 to 0.933) −0.348 −1.057 −28.5 74
    4 0.9729 0.868 (0.823 to 0.913) −0.213 −0.429 −30.2 82
    6B 0.9442 1.433 (1.315 to 1.552) −2.93 2.34 17.6 66
    7F 0.9659 1.076 (1.016 to 1.136) −0.664 −0.262 −5.0 89
    8 0.9025 1.242 (1.120 to 1.365) 0.037 1.284 22.2 80
    9N 0.9608 1.099 (1.027 to 1.171) −0.607 −0.044 −0.8 74
    9V 0.9484 1.19 (1.107 to 1.274) −1.176 −0.277 −6.0 84
    12F 0.9404 1.167 (1.055 to 1.278) −1.165 0.143 1.8 54
    14 0.9565 1.184 (1.104 to 1.263) −1.214 0.258 3.2 78
    18C 0.9652 1.203 (1.125 to 1.280) −0.604 −0.062 −2.3 68
    19F 0.3473 8.933 (7.092 to 10.774) −42.688 2.066 31.0 84
    23F 0.9605 1.294 (1.210 to 1.378) −0.548 0.345 −10.8 75
A vs B
    1 0.6634 0.666 (0.534 to 0.798) 1.661 −0.002 0.0 82
    3 0.7889 0.521 (0.435 to 0.608) −0.097 −1.814 −67.7 74
    4 0.7399 0.679 (0.564 to 0.795) 0.2 −0.246 −19.4 82
    6B 0.7852 0.651 (0.536 to 0.766) 1.07 −1.783 −24.5 63
    7F 0.6731 0.468 (0.375 to 0.561) 0.612 −2.088 −51.8 90
    8 0.675 0.889 (0.726 to 1.052) 0.841 0.385 9.0 82
    9N 0.5103 0.314 (0.212 to 0.416) 1.368 −1.706 −47.0 76
    9V 0.6744 1.117 (0.922 to 1.312) −0.961 −0.458 −11.3 84
    12F 0.8121 0.255 (0.215 to 0.294) 1.074 −1.728 −59.7 82
    14 0.6983 0.685 (0.557 to 0.813) −0.442 −2.846 −45.8 80
    18C 0.6609 3.925 (3.232 to 4.619) −2.437 4.749 98.3 74
    19F 0.2223 5.84 (4.584 to 7.096) −22.998 2.275 35.8 84
    23F 0.7496 0.939 (0.776 to 1.102) 0.07 −0.052 −2.6 69
B vs C
    1 0.582 0.404 (0.296 to 0.513) 3.124 −0.698 −11.5 75
    3 0.7661 0.548 (0.455 to 0.641) 0.332 −0.916 −39.8 78
    4 0.8504 1.024 (0.899 to 1.148) 0.249 0.27 26.6 82
    6B 0.7465 0.354 (0.283 to 0.425) 2.467 −3.663 −47.9 70
    7F 0.6902 0.304 (0.241 to 0.366) 1.448 −2.676 −58.4 89
    8 0.4425 0.296 (0.185 to 0.407) 2.947 −1.668 −29.1 76
    9N 0.5121 0.305 (0.207 to 0.404) 1.459 −1.466 −42.1 77
    9V 0.7287 0.522 (0.429 to 0.615) 1.584 −1.025 −20.7 86
    12F 0.8043 0.188 (0.149 to 0.228) 1.667 −3.24 −73.2 51
    14 0.8061 0.422 (0.359 to 0.484) 1.197 −6.302 −64.2 86
    18C 0.6582 0.686 (0.548 to 0.823) 4.825 2.362 26.2 80
    19F 0.7766 1.738 (1.495 to 1.981) 0.267 3.767 56.9 85
    23F 0.9102 0.772 (0.693 to 0.850) 0.225 −0.203 −11.4 73
a

All possible pairwise comparisons of the three assays are shown for each serotype. Regression statistics were calculated by Deming analysis.

b

CI, confidence interval.

c

Average bias is presented as the absolute bias and the percent bias for each comparison.

d

Number of samples which fell within the quantifiable range of the assays in question for a given pairwise comparison.