TABLE 1.
Cytokine production by splenocytes of immunized Kunming mice after stimulation with Toxoplasma lysate antigena
| Mouse group | Cytokine production (mean ± SD) (pg/ml) |
||||
|---|---|---|---|---|---|
| IFN-γ | IL-2 | IL-4 | IL-10 | IL-12(p70) | |
| pVAX-CDPK3 | 982.68 ± 378.22b | 266.04 ± 9.13b | <15 | 136.53 ± 71.63b | 96.84 ± 4.06b |
| pVAX I | 34.91 ± 11.23 | <15 | <15 | 322.50 ± 179.17 | 15.14 ± 7.63 |
| PBS | 36.34 ± 4.83 | <15 | <15 | 356.13 ± 175.27 | 22.31 ± 4.40 |
| Blank control | 47.28 ± 16.60 | <15 | <15 | 477.25 ± 87.53 | 25.29 ± 17.35 |
a
Splenocytes from mice were harvested 2 weeks after the final immunization.
b
Statistically significant difference (P < 0.05).