TABLE 2.

Susceptibility testing against different Cryptococcus molecular types and subtypes

Molecular type (no. of isolates)	Parameter	MIC (μg/ml)
		Fluconazole	Itraconazole	Posaconazole	Voriconazole	Amphotericin B	Flucytosine
VGI (10)	MIC range	1 to 8	1 to 2	0.5 to 2	0.03 to 1	0.25 to 0.5	0.125 to 0.5
	GM MIC	2.30	1.32	0.81	0.06	0.38	0.25
	MFC range	4 to >64	2 to 16	1 to 4	0.125 to 4	0.25 to 0.5	2 to >64
VGIIa (9)	MIC range	0.5 to 8	0.25 to 2	0.125 to 2	0.03 to 0.125	0.125 to 0.5	0.125 to 2
	GM MIC	3.08	1	0.77	0.07	0.39	0.46
	MFC range	4 to >64	2 to >16	1 to 8	0.5 to 16	0.5 to 1	1 to >64
VGIIb (7)	MIC range	1 to 16	1 to 2	0.5 to 1	0.06 to 0.125	0.25 to 0.5	0.125 to 0.5
	GM MIC	4	1.32	0.76	0.08	0.44	0.25
	MFC range	4 to >64	2 to >16	2 to 4	0.25 to 16	0.25 to 1	4 to >64
VGIIc (4)	MIC range	2 to 16	2 to 4	1 to 2	0.06 to 0.5	0.25 to 0.5	0.25 to 0.5
	GM MIC	8	2.38	1.68	0.18	0.42	0.35
	MFC range	64 to >64	2 to 16	4 to 8	0.25 to >16	0.25 to 1	8 to >64
VGIII (10)	MIC range	2 to 8	1 to 2	1	0.06 to 0.5	0.25 to 0.5	0.125 to >64
	GM MIC	3.48	1.07	0.93	0.06	0.47	0.62
	MFC range	16 to 32	2 to 8	2 to 4	0.125 to 1	0.25 to 1	4 to >64
VGIV (4)	MIC range	2 to 8	1 to 2	1	0.06 to 0.5	0.25 to 0.5	0.125 to 0.5
	GM MIC	4	1.52	1	0.11	0.44	0.19
	MFC range	4 to >64	1 to 16	2 to 4	0.25 to >16	0.25 to 0.5	4 to >64
VNI (5)	MIC range	1 to 2	1 to 2	0.25 to 1	0.03 to 0.125	0.5	0.125 to 0.5
	GM MIC	1.74	1.52	0.66	0.05	0.5	0.33
	MFC range	8 to >64	2 to 8	2 to 4	0.25 to >16	0.5	2 to >64