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CpxR activates vexRAB and vexGH expression in the absence of RND efflux activity. V. cholerae strains containing a vexRAB (A) or vexGH (B) reporter plasmid were grown under AKI growth conditions. Aliquots were taken at 3.5 and 6.5 h and assayed for β-galactosidase activity. The presented data are the means ± SD of results from three independent experiments. Statistical significance was determined by ANOVA with the Tukey-Kramer multiple-comparison test. *, P < 0.001.
