FIG 9.
Adhesion of T. foetus to intestinal epithelial monolayers is mediated by cysteine protease activity. Adhesion of [3H]thymidine-labeled T. foetus to IPEC-J2 monolayers is significantly reduced following pretreatment of trichomonads with the cysteine protease inhibitor E64 compared to vehicle-treated (dH20) T. foetus. No effect is observed on T. foetus adhesion following pretreatment using protease inhibitors of other classes. *, P < 0.05 compared to vehicle-treated T. foetus (Mann-Whitney rank-sum test). Each data point represents 4 to 11 cultures per treatment.