FIG 2.

Macrophage chemokine secretion induced by infection with SH and CHR strains. Shown are kinetics of CCL8 (A) and CXCL5 (B) secretion in human primary macrophages obtained from healthy donors (n = 6) after 8 to 72 h of infection with L. panamensis strains isolated from patients with self-healing CL (L.p.2272sh) and from those with chronic disease (L.p.5397chr and L.p.2504chr). Data are expressed as means ± standard errors of the means. Statistical significance was estimated by using Kruskal-Wallis one-way analysis of variance followed by Dunn's test for multiple comparisons. *, P < 0.05 compared to the uninfected control.