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. 2014 Jul;34(14):2695–2709. doi: 10.1128/MCB.01705-12

FIG 7.

FIG 7

TRIM24 is a direct gene target of p53. (A) p53 ChIP analysis in human cells. p53-bound chromatin was immunoprecipitated from MCF7 cells treated with Adr for 12 h, and p53 enrichment on TRIM24, MDM2, and CDKN1A was analyzed by qPCR using primers encompassing p53REs and plotted as the fold increase in p53 enrichment compared to input. (B) p53 ChIP analysis in mouse ES cells. p53-bound chromatin was immunoprecipitated from mES cells treated with Adr for 5 or 12 h, and p53 enrichment on Trim24, Mdm2, and Cdkn1a was analyzed by qPCR using primers encompassing p53REs and plotted as the fold increase in p53 enrichment compared to input.