TABLE 1.
Estimates of actin incorporation into HIV-1 particles derived from different cell typesa
Parameter | Value for cell type |
||
---|---|---|---|
HEK293T | MT-4 | CD4+ T | |
Cell vol (μm3) | 402 | 546 | 183 |
Actin level/cell (pg) | 1.3 | 3.4 | 2.5 |
Actin concn/cell (μM) | 77 | 117 | 327 |
Molar ratio of CA/actin in virions | ∼110 | ∼220 | ∼20 |
Actin concn/virion (μM) | 23 | 11 | 130 |
Ratio of actin concn (virion/cell) | 0.3 | 0.09 | 0.4 |
No. of actin molecules per virion | ∼22 | ∼11 | ∼125 |
For details, see Materials and Methods.