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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Nat Rev Genet. 2012 Dec;13(12):853–866. doi: 10.1038/nrg3336
Phenotypic Feature (Examples) Human Lineage Specific Trait Possible Evolutionary Advantages
Brain growth trajectory Prolonged postnatal brain growth and delayed myelinization period; Enhanced cognition Allowed creation of novel solutions to survival threats, increased the critical period of learning new skills, and facilitated emergence of uniquely human cognitive skills
Brain size Increased brain-body size ratio; Enhanced cognition Allowed creation of novel solutions to survival threats and improved social cognition.
Descended Larynx Portion of tongue resides in throat at level of pharynx. Larynx descended into throat Helped enable spoken language
Eccrine sweat gland density Higher density of eccrine glands; enhanced sweating capacity Enhanced cooling ability; protection of heat-sensitive tissues (e.g. brain) against thermal stress. Facilitated endurance running.
Endurance running Improved energy utilization during periods of high energy demand; Increased capacity to transfer energy (glycerol) from fat stores to muscle; Anatomical changes relating to running ability Allowed persistence hunting to emerge as a viable strategy for accessing the benefits of increased meat consumption
Increased range of food sources
Improved diet may have facilitated brain evolution
Labor Earlier onset and longer duration of labor Partially protected child/mother from damage due to increased head circumference
Lacrimation Emotional lacrimation (Crying) Enhance emotional communication within social groups
Increased affective communication
T cell function Relative T cell hyperreactivity Enhanced immune function
Thumb Increased length, more distally placed, larger associated muscles Created more detailed tools
Manipulated objects on finer scale