Table I.

Physical features, services received, and medical and psychiatric diagnoses in XYY males, by prenatal vs postnatal ascertainment

	Prenatal	Postnatal	Combined	P value*	Prevalence in childhood
N	35	55	90
Age, y	8.2 ± 5.4	10.5 ± 5.1	9.6 ± 5.3	.05
(mean ± SD, range)	0.5-21.5	2.8-36.5	0.5-36.5
SES	52 ± 10	47 ± 11	49 ± 11	.05
Measurements
Height SDS (mean ± SDS)	0.9 ± 1.3	1.0 ± 1.2	1.0 ± 1.2	.72
Weight SDS	0.6 ± 1.4	0.9 ± 1.2	0.8 ± 1.3	.40
BMISDS	0.5 ± 1.1	0.5 ± 1.2	0.5 ± 1.2	.95
HC SDS	1.3 ± 1.6	1.3 ± 1.7	1.3 ± 1.6	.97
WC >90 percentile for age	19%	19%	19%		10%
Testicular volume SDS (right)	2.0 ± 2.5	2.1 ± 2.2	2.0 ± 2.3	.88
Penile length SDS	—0.6 ± 1.4	—0.5 ± 1.4	—0.5 ± 1.4	.76
Features
Hypotonia	51%	71%	63%	.08
Low musculature	20%	20%	20%	.99
Clinodactyly	46%	57%	52%	.39	<10%
Hypertelorism	53%	64%	59%	.38
Tremor	41%	45%	43%	.83	0.1%-22%
Dental problems	29%	18%	22%	.30
Flat feet	44%	59%	53%	.19
Scoliosis	9%	16%	13%	.36	4%
Services
OT or PT	59%	70%	66%	.36
Other special education	23%	52%	43%	.01
Speech therapy	64%	94%	83%	.01
Medical diagnoses
Motor delay/dyspraxia	23%	18%	20%	.60	<5%
Asthma	44%	36%	39%	.51	9.6%
Seizures	3%	20%	13%	.03	1%
Psychiatric diagnoses
ADD or ADHD	40%	60%	52%	.08	2%-16%
Verbal or motor tic	18%	18%	18%	.99	5%-10%
Oppositional defiant	6%	5%	6%	.99	1%-16%
Depression	11%	15%	13%	.76	<1%
Anxiety	17%	31%	26%	.22	15%-20%
ASD/pervasive Developmental disorder	11%	40%	29%	.004	1%
Bipolar	0%	13%	8%	.04	0.4%-6.3%

OT,occupational therapy; PT,physical therapy; ADD, attention deficit disorder; N, number. Bolded values are P < .05.

^*Pvalue, prenatal vs postnatal.