Table 4. Bootstrapped Linear Regression Models Examining the Association Between a Priori ROI 2-Back>0-Back Activation & Waist Circumference.
| Brain Region & MNI Coordinates (X, Y, Z) | Estimate ± SE | p-value | 95% CIs |
|---|---|---|---|
|
| |||
| Left Middle Frontal Gyrus (-33, 8, 58) | 0.025 | ||
| Age | -0.025±0.009 | 0.008 | -0.042 – -0.009 |
| Sex | 0.137±0.112 | 0.219 | -0.074 – 0.379 |
| Systolic Blood Pressure | 0.011±0.005 | 0.018 | 0.002 – 0.021 |
| Total Cholesterol | 0.001±0.001 | 0.432 | -0.002 – 0.004 |
| Waist Circumference | -0.009±0.005 | 0.095 | -0.020 – 0.001 |
|
| |||
| Left Medial Frontal Gyrus (-4, 24, 43) | 0.032 | ||
| Age | -0.009±0.005 | 0.080 | -0.020 – 0.000 |
| Sex | 0.180±0.089 | 0.052 | 0.024 – 0.366 |
| Systolic Blood Pressure | 0.004±0.002 | 0.085 | 0.000 – 0.009 |
| Total Cholesterol | 0.000±0.001 | 0.966 | -0.002 – 0.002 |
| Waist Circumference | -0.006±0.003 | 0.045 | -0.012 – -0.001 |
|
| |||
| Right Superior Parietal Lobule (40, -62, 59) | 0.061 | ||
| Age | -0.011±0.011 | 0.275 | -0.032 – 0.011 |
| Sex | 0.382±0.152 | 0.016 | 0.101 – 0.683 |
| Systolic Blood Pressure | 0.010±0.005 | 0.047 | 0.001 – 0.021 |
| Total Cholesterol | 0.002±0.002 | 0.379 | -0.002 – 0.005 |
| Waist Circumference | -0.009±0.005 | 0.100 | -0.019 – 0.001 |
|
| |||
| Left Inferior Parietal Lobule (-50, -51, 49) | 0.450 | ||
| Age | -0.007±0.007 | 0.316 | -0.020 – 0.006 |
| Sex | 0.094±0.086 | 0.280 | -0.082 – 0.261 |
| Systolic Blood Pressure | 0.004±0.004 | 0.341 | -0.003 – 0.012 |
| Total Cholesterol | -0.001±0.001 | 0.317 | -0.003 – 0.001 |
| Waist Circumference | -0.005±0.004 | 0.140 | -0.013 – 0.002 |
|
| |||
| Left Middle Frontal Gyrus (-45, 48, 8) | 0.003* | ||
| Age | -0.009±0.007 | 0.191 | -0.021 – 0.005 |
| Sex | 0.275±0.085 | 0.002* | 0.099 – 0.437 |
| Systolic Blood Pressure | 0.005±0.003 | 0.096 | -0.001 – 0.012 |
| Total Cholesterol | -0.001±0.001 | 0.280 | -0.003 – 0.001 |
| Waist Circumference | -0.009±0.003 | 0.002* | -0.015 – -0.003 |
|
| |||
| Right Superior Frontal Gyrus (36, 52, 9) | <0.001* | ||
| Age | -0.005±0.004 | 0.243 | -0.013 – 0.003 |
| Sex | 0.219±0.052 | 0.001* | 0.121 – 0.325 |
| Systolic Blood Pressure | 0.006±0.002 | 0.006* | 0.002 – 0.009 |
| Total Cholesterol | 0.000±0.001 | 0.810 | -0.001 – 0.001 |
| Waist Circumference | -0.008±0.002 | 0.001* | -0.012 – -0.004 |
|
| |||
| Right Middle Frontal Gyrus (35, 10, 56) | 0.300 | ||
| Age | -0.017±0.010 | 0.099 | -0.038 – 0.005 |
| Sex | 0.208±0.142 | 0.132 | -0.080 – 0.494 |
| Systolic Blood Pressure | 0.009±0.006 | 0.151 | -0.003 – 0.020 |
| Total Cholesterol | 0.001±0.001 | 0.693 | -0.002 – 0.003 |
| Waist Circumference | -0.004±0.006 | 0.449 | -0.016 – 0.008 |
|
| |||
| Right Inferior Frontal Gyrus (51, 16, -2) | 0.654 | ||
| Age | 0.005±0.005 | 0.267 | -0.005 – 0.016 |
| Sex | 0.031±0.070 | 0.663 | -0.108 – 0.167 |
| Systolic Blood Pressure | 0.001±0.002 | 0.570 | -0.003 – 0.006 |
| Total Cholesterol | -0.001±0.001 | 0.282 | -0.003 – 0.001 |
| Waist Circumference | -0.002±0.002 | 0.274 | -0.007 – 0.002 |
*
p<0.0062 based on bootstrapping results