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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: J Magn Reson Imaging. 2013 Dec 31;41(1):102–109. doi: 10.1002/jmri.24550

Figure 1.

Figure 1

A: Representative axial slice of lesion probability map (LPM) in each group based on MRI T2-FLAIR images showed a peri-ventricular WM lesion distribution. Compared with controls (A1), LPM in MCI (A2), and AD (A3) groups showed significantly increased WM lesions in especially the left periventricular WM around the occipital horn and frontal WM. B: Amyloid imaging using PET [18F]-Florbetapir tracer in the normal control (B1), MCI (B2), and AD (B3) subjects showed increased amyloid deposition patterns in MCI patients in medial frontal and parietal regions; and increased uptake in almost the whole brain in AD patients. Amyloid deposition was averaged across subjects in each group after normalizing with the maximal value individually.