Table II.

Correlation coefficients for B-factor prediction obtained by optimal FRI (opFRI), parameter free FRI (pfFRI), and Gaussian normal mode (GNM) for small-size structures.

PDB ID	N	opFRI	pfFRI	GNMa	NMAa
1AIE	31	0.588	0.416	0.155	0.712
1AKG	16	0.373	0.350	0.185	−0.229
1BX7	51	0.726	0.623	0.706	0.868
1ETL	12	0.710	0.609	0.628	0.355
1ETM	12	0.544	0.393	0.432	0.027
1ETN	12	0.089	0.023	−0.274	−0.537
1FF4	65	0.718	0.613	0.674	0.555
1GK7	39	0.845	0.773	0.821	0.822
1GVD	52	0.781	0.732	0.591	0.570
1HJE	13	0.811	0.686	0.616	0.562
1KYC	15	0.796	0.763	0.754	0.784
1NOT	13	0.746	0.622	0.523	0.567
1O06	20	0.910	0.874	0.844	0.900
1OB4	16	0.776	0.763	0.750b	0.930
1OB7	16	0.737	0.545	0.652b	0.952
1P9I	29	0.754	0.742	0.625	0.603
1PEF	18	0.888	0.826	0.808	0.888
1PEN	16	0.516	0.465	0.270	0.056
1Q9B	43	0.746	0.726	0.656	0.646
1RJU	36	0.517	0.447	0.431	0.235
1U06	55	0.474	0.429	0.434	0.377
1UOY	64	0.713	0.653	0.671	0.628
1USE	40	0.438	0.146	−0.142	−0.399
1VRZ	21	0.792	0.695	0.677b	−0.203
1XY2	8	0.619	0.570	0.562	0.458
1YJO	6	0.375	0.333	0.434	0.445
1YZM	46	0.842	0.834	0.901	0.939
2DSX	52	0.337	0.333	0.127	0.433
2JKU	35	0.805	0.695	0.656	0.850
2NLS	36	0.605	0.559	0.530	0.088
2OL9	6	0.909	0.904	0.689	0.886
2OLX	4	0.917	0.888	0.885	0.776
6RXN	45	0.614	0.574	0.594	0.304

^aGNM and NMA values are taken from the coarse-grained (Cα) GNM and NMA results reported in Park et al.²⁸

^bValues indicate correlation coefficients, from our own test of GNM, that have significantly increased compared to the values reported by Park et al.²⁸ See Sec. III C for details regarding the calculation of new GNM scores.