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. 2014 Jul 14;55(7):4327–4337. doi: 10.1167/iovs.14-14606

Figure 8.

Figure 8

Effects of HG and Cx43 downregulation on Akt activity in Müller cells and cocultures of rMC-1 and pericytes. (A) Representative Western blot shows p-Akt and Akt expression in rMC-1. (B) Graphical representation of Western blot data. The ratios of p-Akt to Akt were significantly decreased in cells grown in HG medium and in cells grown in N medium transfected with Cx43 siRNA compared with nontransfected cells or cells transfected with Scram siRNA and grown in N medium. n = 6. (C) Representative Western blot shows p-Akt and Akt expression in cocultures of rMC-1 and pericytes. (D) Graphical representation of Western blot data shows ratios of p-Akt to Akt were significantly decreased in cells grown in HG medium and in cells grown in N medium transfected with Cx43 siRNA compared with nontransfected cells or cells transfected with scrambled siRNA and grown in N medium, n = 6. Data are expressed as mean ± SD. **P < 0.01.