Table 1:
Demographic and Clinical Characteristics of the Lung Disease Subjects That Had Plasma CXCL13 Concentration Assays
| IPF | COPD | |
|---|---|---|
| N | 95 | 128 | 
| Age, yr | 69 ± 1 (70, 51–84) | 65 ± 1 (66, 47–81)* | 
| Sex, % male | 74 | 50* | 
| FVC % predicted | 66 ± 2 (65, 25–126) | 88 ± 2 (89, 38–144)* | 
| FEV1 % predicted | 78 ± 2 (76, 31–133) | 65 ± 2 (67, 12–130)* | 
| FEV1/FVC | 0.84 ± 0.01 (0.84, 0.71–1.22) | 0.55 + 0.01 (0.59, 0.15–0.83)* | 
| DlCO %predicted | 50 ± 2 (49, 14–109) | 60 ± 2 (61, 17–122)* | 
| %-910 HU | ND | 27.8 + 1.8 (23.4, 0.6–73.3) | 
| Smoking history, % | 53 | 100* | 
Definitions of abbreviations: %-910 HU = percentages of lung pixel values less than 910 Hounsfield Units; COPD = chronic obstructive pulmonary disease; CXCL13 = C-X-C motif chemokine 13; DlCO = diffusing capacity of carbon monoxide; IPF = idiopathic pulmonary fibrosis; ND = not determined.
Data are depicted as means ± SE, and in parenthesis (median, minimum-to-maximum ranges). Smoking history denotes subjects with ≥5 pack-years of cigarette smoking.
P ≤ 0.001 for comparisons between the IPF and COPD cohorts.