Table 2:

Demographic and Clinical Characteristics of the Lung Disease Cohorts for the Intrapulmonary CXCL13 mRNA Expression Studies

	IPF	COPD
N	92	191
Age, yr	65 ± 1 (65, 37–80)	64 ± 1 (65, 28–84)
Sex, % male	71*	55
FVC % predicted	65 ± 2 (65, 21–99)*	71 ± 1 (72, 13–121)*
FEV1 % predicted	73 ± 2 (74, 26–110)*	45 ± 1 (47, 11–79)*
DlCO % predicted	50 ± 2 (51, 16–95)	53 ± 2 (49, 13–115)
Smoking history, %	64	100*

Definitions of abbreviations: COPD = chronic obstructive pulmonary disease; CXCL13 = C-X-C motif chemokine 13; Dl_CO = diffusing capacity of carbon monoxide; IPF = idiopathic pulmonary fibrosis.

The specimens used here were obtained from the Lung Tissue Research Consortium (42) and analyzed by DNA microarray at the University of Pittsburgh. The methods and results of these assays are archived in a publicly accessible online database (41).

Data are depicted as means ± SE, and in parenthesis (median, minimum-to-maximum ranges). Smoking history denotes subjects with smoking histories >100 cigarettes.

^*P ≤ 0.01 for comparisons with the other cohort.