Table 3:
Demographic and Clinical Characteristics of IPF Subjects Stratified by Plasma CXCL13 Levels
Lowest CXCL13 | Highest CXCL13 | |
---|---|---|
N | 71 | 24 |
Age, yr | 69 ± 1 (69, 53–84) | 69 ± 2 (72, 51–82) |
Sex, % male | 76 | 67 |
Lung biopsy, % | 56 | 50 |
FVC % predicted | 67 ± 2 (67, 31–126) | 61 ± 4 (59, 25–97) |
DlCO % predicted | 51 ± 2 (50, 20–109) | 46 ± 5 (44, 14–91) |
Smoking history, % | 55 | 48 |
Definitions of abbreviations: CXCL13 = C-X-C motif chemokine 13; DlCO = diffusing capacity of carbon monoxide; IPF = idiopathic pulmonary fibrosis.
Highest CXCL13 denotes those subjects with IPF with mediator values in the highest quartile. Data are depicted as means ± SE, and in parenthesis (median, minimum-to-maximum ranges). None of these characteristics differed significantly between the two subpopulations.