Table 3:
Distribution of MIC of Colistin for Pseudomonas aeruginosa
| Colistin Group |
Placebo Group |
|||||||
|---|---|---|---|---|---|---|---|---|
| N | MIC50 | MIC90 | MIC Range | N | MIC50 | MIC90 | MIC Range | |
| Baseline | 73 | 0.25 | 1.5 | 0.032–2.0 | 70 | 0.5 | 2.0 | 0.047–2.0 |
| 1 mo | 44 | 0.38 | 1.5 | 0.064–2.0 | 49 | 0.5 | 2.0 | 0.064–3.0 |
| Final visit | 47 | 0.25 | 1.5 | 0.047–3.0 | 53 | 0.38 | 1.5 | 0.047–2.0 |
Definition of abbreviations: MIC = minimum inhibitory concentration; MIC50 = minimum inhibitory concentration required to inhibit the growth of 50% of isolates; MIC90 = minimum inhibitory concentration required to inhibit the growth of 90% of isolates; N = number of patient sputum samples with P. aeruginosa.
MIC in milligrams per liter.
Breakpoint MICs for colistin: susceptible ≤4; resistant >4 (35).