Table 2:
PGIS Promoter VNTR Repeat Length and SNP Genotype and Allele Frequencies
| Number | Frequency | |
|---|---|---|
| VNTR genotypes | ||
| 3/4 | 0 | 0.000 |
| 4/4 | 2 | 0.022 |
| 4/5 | 0 | 0.000 |
| 4/6 | 13 | 0.144 |
| 4/7 | 0 | 0.000 |
| 4/8 | 1 | 0.011 |
| 5/5 | 1 | 0.011 |
| 5/6 | 16 | 0.178 |
| 5/7 | 0 | 0.000 |
| 5/8 | 0 | 0.000 |
| 6/6 | 49 | 0.544 |
| 6/7 | 5 | 0.056 |
| 6/8 | 2 | 0.022 |
| 6/9 | 1 | 0.011 |
| Total | 90 | 1.000 |
| VNTR alleles | ||
| 3 | 0 | 0.000 |
| 4 | 18 | 0.100 |
| 5 | 18 | 0.100 |
| 6 | 135 | 0.750 |
| 7 | 5 | 0.028 |
| 8 | 3 | 0.017 |
| 9 | 1 | 0.006 |
| Total | 180 | 1.000 |
| SNP1 K22 genotypes | ||
| T/T | 26 | 0.289 |
| T/G | 51 | 0.567 |
| G/G | 13 | 0.144 |
| Total | 90 | 1.000 |
| SNP1 K22 alleles | ||
| T | 103 | 0.572 |
| G | 77 | 0.428 |
| Total | 180 | 1.000 |
| SNP3 Y185 genotypes | ||
| C/C | 27 | 0.300 |
| C/T | 48 | 0.533 |
| T/T | 15 | 0.167 |
| Total | 90 | 1.000 |
| SNP3 Y185 alleles | ||
| C | 102 | 0.567 |
| T | 78 | 0.433 |
| Total | 180 | 1.000 |
| SNP4 C325A genotypes | ||
| C/C | 75 | 0.833 |
| C/A | 14 | 0.156 |
| A/A | 1 | 0.011 |
| Total | 90 | 1.000 |
| SNP4 C325A alleles | ||
| C | 164 | 0.911 |
| A | 16 | 0.089 |
| Total | 180 | 1.000 |
Definition of abbreviations: SNP = single-nucleotide polymorphism; PGIS = prostacyclin synthase; VNTR = variable number of tandem repeats.