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Matrigel enhances cellular morphology of primary human hepatocyte cultures for donor A, donor B, and donor C. Primary human hepatocytes from donor A (A and B), donor B (C and D), and donor C (E and F) were cultured in the presence (B, D, F) and absence (A, C, E) of a Matrigel overlay. Photomicrographs were taken under ×20 magnification using phase contrast imaging. Arrows indicate compromised morphology in the absence of a Matrigel overlay.
