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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Toxicol Sci. 2007 Feb 27;97(2):384–397. doi: 10.1093/toxsci/kfm034

TABLE 6.

Selected GO Terms from Increased Gene List among All Human Hepatocyte Samples

Best GOs GO descriptions Count
(1621)		 Total
(13,410)		 p Value
GO:0016491 Oxidoreductase activity 187 569 6.00 × 10−51
GO:0016614 Oxidoreductase activity, acting on CH-OH group of donors 46 96 4.38 × 10−24
GO:0016616 Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 43 88 3.30 × 10−23
GO:0016705 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 40 102 1.63 × 10−14
GO:0016627 Oxidoreductase activity, acting on the CH-CH group of donors 22 43 2.00 × 10−12
GO:0004497 Monooxygenase activity 32 85 8.96 × 10−11
GO:0016628 Oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 12 15 1.33 × 10−07
GO:0042221 Response to chemical stimulus 69 314 3.34 × 10−06
GO:0016709 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen 12 20 1.55 × 10−05
GO:0006805 Xenobiotic metabolism 13 25 4.26 × 10−05
GO:0009410 Response to xenobiotic stimulus 13 27 0.000122

Note. All increased probe sets for all five donors were combined and batch analyzed by GOstat (Beissbarth and Speed, 2004). Results show the confidence level associated with the GO term overrepresentation.