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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Int J Oncol. 2009 Aug;35(2):337–345.

Figure 2.

Figure 2

MUC1 functions to drive cell survival and colony formation. (A) Cells were exposed to siRNA for 120 h, and proliferation rates were measured by MTT assay. *P<0.01, **P<0.05 compared with the control. (B) Cells were exposed to siRNA for 72 h, and cell apoptosis evidenced by positive cells of active caspase-3 in the cells was assessed by flow cytometry analysis. Relative units of apoptosis for the control were set to 1; data for the MUC1 siRNA are shown as fold change relative to control siRNA. (C) Cells treated with siRNA were grown in RPMI-1640 medium supplied with 10% FBS, and colonies were counted after 14 days. *P<0.01, **P<0.05 compared with the control.