Table 3. HRs and 95% CIs for Kidney Cancer Incidence for Different Categories of BP, Modeled Within BMI Strata in WHI.
Models are adjusted for age, smoking and race/ethnicity.
| BMI (kg/m2) | Blood Pressure (mmHg) |
Individuals at risk (number) |
Cancer cases (number) |
% that developed cancer |
HR (95% CI) |
|---|---|---|---|---|---|
| Models examining SBP | |||||
| BMI <25 | SBP <140 | 44,284 | 84 | 0.19 | 1.00 |
| SBP 140–159 | 7,712 | 18 | 0.23 | 1.12 (0.67, 1.89) | |
| SBP ≥160 | 2,218 | 6 | 0.27 | 1.25 (0.54, 2.91) | |
| BMI 25.0–29.9 | SBP <140 | 42,007 | 98 | 0.23 | 1.00 |
| SBP 140–159 | 10,054 | 42 | 0.42 | 1.66 (1.14, 2.40) | |
| SBP ≥160 | 2,798 | 4 | 0.14 | 0.55 (0.20, 1.49) | |
| BMI ≥30 | SBP <140 | 34,027 | 91 | 0.27 | 1.00 |
| SBP 140–159 | 10,880 | 49 | 0.45 | 1.67 (1.17, 2.38) | |
| SBP ≥160 | 2,727 | 14 | 0.51 | 1.94 (1.07, 3.50) | |
| Models examining DBP | |||||
| BMI <25 | DBP <90 | 51,657 | 101 | 0.20 | 1.00 |
| DBP ≥90 | 2,551 | 7 | 0.27 | 1.47 (0.68, 3.17) | |
| BMI 25.0–29.9 | DBP <90 | 51,172 | 137 | 0.27 | 1.00 |
| DBP ≥90 | 3,675 | 7 | 0.19 | 0.76 (0.36, 1.63) | |
| BMI ≥30 | DBP <90 | 43,193 | 132 | 0.31 | 1.00 |
| DBP ≥90 | 4,433 | 22 | 0.50 | 1.75 (1.11, 2.76) | |