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MyBP-C mRNA and protein expression levels in hearts of 12-week-old homozygous MyBP-C(Neo) mice (designated t/t). (a) Northern blot analyses of RNAs from left ventricle of wild-type (+/+) and MyBP-C(Neo) mice hybridized with murine MyBP-C and GAPDH probes. (b) Western blot analyses identified the 150-kDa MyBP-C protein in myofibrillar extracts of the LV of wild-type (+/+) and homozygous MyBP-C(Neo) mice (t/t).
