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Comparison of hearts from 8–12-week-old wild-type and homozygous mutant mice. (a) Gross morphology of homozygous MyBP-C(Neo) (designated t/t) and wild-type (+/+) hearts and (b) heart-to-body weight or LV-to-body weight ratios demonstrate significant increases (P < 0.001) in cardiac size of homozygous mutant mice (t/t) versus wild-type mice (+/+).
